A 55-year-old male presents to the emergency department with crushing chest pain for the past 45 minutes. His ECG is shown. Based on the findings, what is the most likely diagnosis?

Question

BlackTom AI · Accepted Answer

ST-segment elevation localized to the precordial leads indicates an acute transmural infarction of the anterior wall of the left ventricle, most commonly due to occlusion of the left anterior descending (LAD) coronary artery — acute anterior myocardial infarction.

1) Relevant knowledge points and concepts
- Transmural (full-thickness) myocardial ischemia produces ST-segment elevation in the ECG leads that view the injured region.  
- Anterior wall is represented by leads V1–V4 (sometimes V5–V6 for anterolateral).  
- Inferior MI shows ST-elevation in II, III, aVF.  
- Acute pericarditis causes diffuse (widespread) concave ST-elevation with PR depression, not localized to contiguous lead groups.  
- Early repolarization (benign) shows mild, concave ST-elevation and prominent T waves in young healthy patients, typically without ischemic symptoms or reciprocal ST depression.

2) Step-by-step reasoning process
- Clinical context: 55-year-old male with crushing chest pain for 45 minutes — high pre-test probability of acute coronary syndrome.  
- ECG inspection: ST-segment elevation confined to the anterior/precordial leads (V1–V4). The morphology in acute anterior MI is often convex ("tombstone") or marked elevation, and there may be reciprocal ST depression in inferior leads. Q waves may develop later; early ECG shows ST elevation without Q waves.  
- Correlate ECG with anatomy: ST elevation in V1–V4 maps to the anterior wall supplied by the LAD, hence anterior MI.

3) Intermediate steps / calculations
- No numeric calculations are needed. The diagnostic steps are pattern recognition: identify which leads have ST elevation, assess distribution (contiguous anterior leads), and combine with clinical presentation (acute chest pain).

4) Why the correct answer is correct
- The ECG shows localized ST elevation in anterior leads consistent with acute transmural ischemia of the anterior wall — the defining feature of an acute anterior myocardial infarction.

5) Why the other options are incorrect
- Acute inferior MI: would show ST elevation in II, III, aVF, not isolated anterior leads.  
- Acute pericarditis: produces diffuse ST elevation across many leads plus PR depression, rather than focal anterior changes; clinical picture often pleuritic chest pain relieved by sitting forward.  
- Early repolarization: typically benign, seen in younger patients, with widespread mild concave ST elevation, not associated with severe crushing chest pain and not limited to contiguous anterior leads.

Conclusion: The ECG pattern and clinical presentation are diagnostic of an acute anterior myocardial infarction — confirming the provided answer: Acute anterior myocardial infarction.

A 55-year-old male presents to the emergency department with crushing chest pain for the past 45 minutes. His ECG is shown. Based on the findings, what is the most likely diagnosis? 单项选择题

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