Question at position 7 Increased aldosterone would cause:increased reabsorption of Na+increased permeability of the DCT to waterdecreased blood volumedecreased reabsorption of Cl-

Question

Question at position 7 Increased aldosterone would cause:increased reabsorption of Na+increased permeability of the DCT to waterdecreased blood volumedecreased reabsorption of Cl-

BlackTom AI · Accepted Answer

Let's evaluate each option in light of how aldosterone functions in the renal tubules.
Option 1: 'increased reabsorption of Na+' — This is true. Aldosterone acts on principal cells in the distal tubule and collecting duct to upregulate the epithelial sodium channel (ENaC) and Na+/K+ ATPase, promoting Na+ reabsorption from the tubular lumen into the blood, which also helps drive water reabsorption.
Option 2: 'increased permeability of the DCT to water' — Aldosterone does not directly increase water permeability in the distal convoluted tubule. Water movement is largely controlled by aquaporin channels whose insertion is primarily regulated by antidiuretic hormone (ADH). The DCT’s response to aldosterone is mainly through Na+ handling, not water channels.
Option 3: 'decreased blood volume' — In contrast, increasing Na+ (and accompanying water) reabsorption tends to expand extracellular fluid and blood volume. A decrease in blood volume would not be expected with aldosterone’s primary action.
Option 4: 'decreased reabsorption of Cl-' — Chloride reabsorption often accompanies Na+ (electroneutral reabsorption) as Na+ is reabsorbed with accompanying anions like Cl-. Aldosterone’s effect on Na+ reabsorption would not cause a decrease in Cl- reabsorption; if anything, Cl- reabsorption can increase along with Na+. Therefore this statement is incorrect.
In summary, the statement that aligns with aldosterone’s primary renal action is the increased reabsorption of Na+ because aldosterone directly boosts Na+ uptake in the distal nephron, with secondary effects on overall fluid balance.

Question at position 7 Increased aldosterone would cause:increased reabsorption of Na+increased permeability of the DCT to waterdecreased blood volumedecreased reabsorption of Cl-单项选择题

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