What bond being formed during the condensation reaction between the nucleotides in the video?

Question

BlackTom AI · Accepted Answer

The question asks about which bond forms during the condensation (dehydration) reaction that links nucleotides in the video.
Option 1: Ionic bond. Ionic interactions are not the chemical linkage between nucleotides in a DNA or RNA strand; they are electrostatic attractions between charged groups and do not form the backbone linkage.
Option 2: Peptide bond. Peptide bonds connect amino acids in proteins, not nucleotides. This option would be confused with protein synthesis, not nucleic acid polymerization.
Option 3: Hydrogen bond. Hydrogen bonds stabilize base pairing between strands (e.g., A–T and G–C in DNA) but do not form the phosphodiester backbone themselves. They are interactions between bases rather than the backbone linkage.
Option 4: Phosphodiester bond. This is the correct backbone linkage formed when nucleotides condense: a phosphate group from one nucleotide forms an ester linkage with the 3' carbon of the sugar of the next nucleotide, creating a repeating phosphodiester backbone in nucleic acids.
In summary, the condensation reaction that links nucleotides builds the phosphodiester backbone, while the other bond types either serve different roles or are incorrect in this context.

What bond being formed during the condensation reaction between the nucleotides in the video?单项选择题

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