The three major regulatory enzymes in the glycolytic pathway are

Question

BlackTom AI · Accepted Answer

To tackle the question, I will examine each proposed set of enzymes and compare them to the well-established regulatory control points of glycolysis.
Option 1: hexokinase, phosphofructokinase, and pyruvate kinase. This combination lists three enzymes that are classic rate-limiting or highly regulated steps in glycolysis: hexokinase (glucose to glucose-6-phosphate), phosphofructokinase-1 (PFK-1) (fructose-6-phosphate to fructose-1,6-bisphosphate), and pyruvate kinase (phosphoenolpyruvate to pyruvate). These are widely recognized as the three major regulatory enzymes driving flux through the pathway.
Option 2: phosphofructokinase, glyceraldehyde-3-phosphate dehydrogenase, and pyruvate kinase. While PFK-1 and pyruvate kinase are regulatory, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is generally considered a catalytic enzyme with regulated expression/activity, but it is not categorized as one of the major regulatory choke points in glycolysis. This makes the set incorrect as the trio lacks hexokinase and includes a non-primary regulatory enzyme.
Option 3: hexokinase, phosphofructokinase, and phosphoglycerate kinase. Here, hexokinase and PFK-1 are indeed key regulators, but phosphoglycerate kinase is not typically described as a major regulatory choke point in glycolysis; it functions further downstream in energy-yielding steps and is not among the principal regulatory enzymes. Therefore this option is not the standard trio of major regulators.
Option 4: glyceraldehyde-3-phosphate dehydrogenase, pyruvate kinase, hexokinase. This set includes hexokinase and pyruvate kinase, both important, but glyceraldehyde-3-phosphate dehydrogenase is not considered a major regulatory enzyme in the glycolytic control scheme. The absence of phosphofructokinase, the central allosteric regulator of glycolysis, makes this option incorrect.
In summary, only Option 1 accurately lists the three canonical major regulatory enzymes of glycolysis, while the other options replace or omit one of these critical control points and thus fail to reflect the established regulatory hierarchy.

The three major regulatory enzymes in the glycolytic pathway are 单项选择题

类似问题

How many regulatory reactions are there in glycolysis?

What will be the effect of insulin on PFK-1? This will glycolytic flux. ATP is a substrate at low concentration, and a _ at high (accumulating) concentration.

This is the "ring/married" step because _____________ This step is _. The product made is ________.

Which of the following stimulates phosphofructokinase in the liver?

Well into exercise, the ratio of ATP/AMP in muscle cells decreases. What effect does this ratio reduction have on the activity of phosphofructokinase and pyruvate kinase?

Question17 What is the major activator of glycolysis in most cells? Select one alternative: NADH NAD+ FADH2 AMP ATP ResetMaximum marks: 1 Flag question undefined

The enzyme phosphofructokinase (PFK) catalyzes a key step in glycolysis and is inhibited by high levels of which of the following molecules?

Is the following statement true or false? In the products of methylation-hydrolysis, every -OH group corresponds to the position of a glycosidic bond in the starting polysaccharide.

更多留学生实用工具

智能学习助手

风格化写作助手

论文查重助手

文献引用助手

课堂转译助手

课堂笔记助手

Quiz搜索助手

学校历年真题

智能刷题助手

智能匹配练习

希望你的学习变得更简单