Which of the following cells play key roles in supporting the nervous system, and is derived from the neural tube?

Question

BlackTom AI · Accepted Answer

Question restatement: Which of the following cells play key roles in supporting the nervous system, and is derived from the neural tube?

Option 1: Microglia. These are CNS immune cells that originate primarily from the yolk sac (mesodermal/hematopoietic lineage) and migrate into the brain, not from the neural tube. Therefore, they do not fit the neural tube origin criterion.

Option 2: Endothelial cells. These line blood vessels and are derived from mesoderm. Their role is vascular rather than neural support, and they do not arise from the neural tube itself.

Option 3: Meningeal cells. Meninges (including the arachnoid and dura mater) have contributions from multiple embryonic lineages, including mesenchyme and neural crest in various regions. They are not standardized as neural tube derivatives, and their primary function is protective covering rather than intrinsic neural support.

Option 4: Schwann cells. These are glial cells that support the peripheral nervous system by forming myelin sheaths around peripheral nerves. Schwann cells originate from neural crest cells, not from the neural tube itself, so they do not meet the neural tube derivation criterion.

Option 5: None of the others. Given the strict condition that the cell type must both support the nervous system and be derived from the neural tube, none of the above options satisfies both criteria. The neural tube primarily gives rise to CNS neurons and glial cells like oligodendrocytes, not Schwann cells or the other listed cell types.

Summary of reasoning: Each option either misattributes the developmental origin (neural tube vs. neural crest or mesoderm) or misdefines the cell’s primary role in neural support. Microglia are yolk sac–derived, endothelial cells are mesoderm-derived vasculature components, meninges come from mesenchymal/neural crest sources, and Schwann cells come from neural crest, not the neural tube. Therefore, none of the listed options fulfills both criteria (neural tube origin and key supportive role in the nervous system) as stated.

Which of the following cells play key roles in supporting the nervous system, and is derived from the neural tube?单项选择题

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