Evaluate the implications of pharmacogenomic variations in metabolizing enzymes when designing a clinical trial for a new cardiovascular drug.单项选择题

A

It is necessary to standardize genetic backgrounds to avoid skewed data on drug efficacy.

B

Pharmacogenomic variations are irrelevant unless the trial involves genetic therapies.

C

Only the dosage of the drug should be adjusted without considering genetic variations.

D

Genetic variations should not influence the trial design as they are rarely significant.

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