Multiple Choice: Which of the following helminths (parasitic worms) is associated with neurocysticercosis, a rare but severe complication due to the ingestion of helminth eggs, usually from undercooked pork.

Question

BlackTom AI · Accepted Answer

Taenia solium is the tapeworm species responsible for neurocysticercosis because humans can become accidental intermediate hosts when they ingest T. solium eggs, leading to cystic larvae (cysticerci) in the central nervous system.

1) Relevant knowledge points and concepts
- Taenia solium life cycle: pigs normally serve as the intermediate host, carrying cysticerci in muscle; humans become definitive hosts by eating undercooked pork containing cysticerci, which develop into adult tapeworms in the intestine (taeniasis).
- Neurocysticercosis pathogenesis: if humans ingest T. solium eggs (fecal–oral contamination, sometimes from a human tapeworm carrier), eggs hatch into oncospheres that penetrate the intestinal wall, travel via bloodstream, and form cysticerci in brain tissue, causing neurocysticercosis.
- Clinical significance: cysticerci in the CNS produce seizures, headaches, focal deficits, and can be life-threatening.

2) Step-by-step reasoning
- Source of eggs: adult T. solium in a human intestine produces eggs in feces.
- Route to CNS: if eggs are ingested (directly or by auto-infection), they release oncospheres.
- Migration and cyst formation: oncospheres cross into the circulation and lodge in brain tissue, developing into cysticerci that provoke inflammation and neurologic symptoms.
- Therefore, the only helminth that both produces eggs causing cysticerci in humans and is linked to neurocysticercosis is Taenia solium.

3) Intermediate steps / emphasis
- Eating undercooked pork with cysticerci → intestinal taeniasis (adult worm).
- Eating eggs (from fecal contamination) → systemic cysticercosis, including neurocysticercosis.

4) Why the correct answer is correct
- Taenia solium uniquely causes human cysticercosis because humans can act as intermediate hosts for its eggs; the CNS manifestations define neurocysticercosis.

5) Why other helminths would be incorrect
- Taenia saginata (beef tapeworm) causes intestinal taeniasis but does not cause human cysticercosis. Echinococcus spp. cause hydatid cysts (different pathology). Trichinella spiralis causes muscle encystment, not brain cysticerci.

Conclusion: The correct answer is Taenia solium, matching the provided answer.

Multiple Choice: Which of the following helminths (parasitic worms) is associated with neurocysticercosis, a rare but severe complication due to the ingestion of helminth eggs, usually from undercooked pork.单项选择题

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