A patient has chronic cough and weight loss. Sputum shows red bacilli on Ziehl–Neelsen staining. Which feature is most responsible for persistence of this pathogen inside macrophages?单项选择题

A

Pneumolysin-mediated lysis of host cells

B

M protein preventing opsonisation

C

Elastase expression aiding tissue invasion

D

Waxy mycolic acid cell wall

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