For a neuron with an initial membrane potential at -70 mV, what would be the result of an increase in the movement of potassium ions out of that neuron's cytoplasm?

Question

BlackTom AI · Accepted Answer

To approach this, let's consider what happens when there is an increase in potassium ion (K+) efflux from the neuron's cytoplasm.
Option 1: 'replacement of potassium ions with sodium ions' suggests ions are swapped across the membrane, which is not how membrane potential changes occur in response to increased K+ leak. Ionic exchange like that does not describe the physiological mechanism here.
Option 2: 'hyperpolarization of the neuron' correctly captures the effect. More K+ leaving the cell makes the inside more negative relative to the outside, pulling the membrane potential further away from zero and toward the K+ equilibrium potential, which is a hyperpolarizing shift.
Option 3: 'depolarization of the neuron' would require the inside to become less negative (toward or above 0 mV). Increased K+ efflux does the opposite, so this is not accurate in this context.
Option 4: 'replacement of potassium ions with calcium ions' implies a substitution process that does not describe the actual membrane dynamics of enhanced K+ efflux. Calcium ions do not replace intracellular K+ in this scenario.
In summary, when more potassium leaves the cell, the membrane potential becomes more negative, which aligns with hyperpolarization, while the other options mischaracterize the mechanism or outcome.

For a neuron with an initial membrane potential at -70 mV, what would be the result of an increase in the movement of potassium ions out of that neuron's cytoplasm?单项选择题

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