You are a clinical pharmacist working on a hospital medical ward and receive a request to review medications for Amanda Brown, a 56-year-old female who was admitted a day ago. She has undergone a surgery this morning at 7am to fix a nerve problem in her lower back (which she has been suffering from for 8 months) and is currently being managed in the medical ward. A doctor prescribed the patient with the medications listed below and is planning to discharge the patient (if everything goes fine) tomorrow. It is 4pm in the afternoon. Pain score: 5 / 10 Medical history Lower back pain 8 months Osteoarthritis for 2 years Constipation (on and off for a year) Dyspepsia (for 6 months) Social History Lives with family Occupation: Supermarket supervisor Marital Status and Children: Married, 2 adult children Smoker (pack years): No Alcohol - Socially Diet: Eats outside mostly, no time to cook Exercise: Nil Recreational Drug Use: Nil Medication history Ibuprofen 400mg BD PRN (for 8 months) Paracetamol Osteo SR 665mg 2 TDS PRN (for 2 years) Coloxyl with senna 2 PRN Pantoprazole 40 mg 1 mane (for 6 months) Current medications in the ward Tramadol 50 mg QID (Plan to stop upon discharge) (has taken 1 dose this afternoon) Ibuprofen 400mg TDS (has taken 1 dose this afternoon) Paracetamol Osteo SR 665 mg 2 tds Pantoprazole 40 mg 1 mane Discharge medications Celecoxib 200 mg 1 daily for 4 weeks – then review Ibuprofen 400mg TDS for 4 weeks – then review Paracetamol 500 mg and Codeine phosphate 30mg, 2 QID for 4 weeks - then review Pantoprazole 30 mg 1 mane Paracetamol Osteo SR 2 TDS[Fill in the blank] Analyse the information provided and identify THREE medication related problems (MRPs) presented in this case.[Fill in the blank] Four weeks have passed, and Mrs. Brown continues to experience persistent pain. Her general practitioner is considering initiating opioid therapy. What is the general approach to dosing opioids for the management of chronic pain?[Fill in the blank] Mrs. Brown is in your pharmacy with a prescription for Oxycodone 5 mg tablets, quantity 20, take 1 tablet up to four times a day as needed for strong pain relief. She shares her concern about taking oxycodone, explaining that her cousin became addicted to opioid painkillers and is now receiving treatment through a methadone program. She asks you, the pharmacist: "Since methadone is also an opioid, why is it considered an appropriate treatment for opioid dependence". Please respond to Mrs. Brown as if you are talking with her. (Word limit = 150)[Fill in the blank]多项填空题