Leukocytes called monocytes eat LDL (bad cholesterol) and turn into macrophages that develop into a plaque that lines the vascular wall.单项选择题
A
Correct
B
Incorrect

Question

Leukocytes called monocytes eat LDL (bad cholesterol) and turn into macrophages that develop into a plaque that lines the vascular wall.

BlackTom AI · Accepted Answer

The statement describes a sequence involved in the development of atherosclerotic plaques. Monocytes are leukocytes that migrate into the arterial intima and differentiate into macrophages. These macrophages ingest oxidized LDL particles, becoming lipid-laden foam cells, which contribute to the formation of fatty streaks and eventually atherosclerotic plaques that line the vascular wall.

Option 1: 'Correct' — This option aligns with the established mechanism: monocytes ingest LDL, turn into macrophages, form foam cells, and participate in plaque development in the vascular intima. The described process is consistent with pathophysiology of atherosclerosis.

Option 2: 'Incorrect' — This would be false because the described mechanism is a recognized pathway in plaque formation. It would be inaccurate to claim that monocytes do not ingest LDL or that plaques do not form in the vascular wall via macrophage activity. Additionally, the end result is not merely a temporary change but a chronic plaque that can affect vessel integrity and function.

Leukocytes called monocytes eat LDL (bad cholesterol) and turn into macrophages that develop into a plaque that lines the vascular wall.单项选择题

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