In this mechanism, lysine is acting as a _________________. Glutamate is acting as a ____________. The __________ is the leaving group. What is the reason Glu/Lys can exist in these states (Glu having an H & lysine being de-protonated)?单项选择题

题目图片
A

acid, base, OH-, the pH is VERY high

B

base, acid, H:-, the pKa of lysine is raised & the pKa of Glu is dropped

C

acid, base, H2O, the pH is VERY low

D

base, acid, H2O, pKa (microenvironment)

E

base, acid, H2O, the pH is VERY low

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