47. The original, common, or “normal” version of a gene is called the _________ type allele.

Question

47. The original, common, or “normal” version of a gene is called the  _________ type allele.

BlackTom AI · Accepted Answer

Wild-type refers to the original, common, or “normal” version of a gene.

1) Relevant knowledge points and concepts
- Allele: a specific version of a gene at a given locus. Individuals can carry different alleles that produce different phenotypes.
- Wild-type allele: the phenotype or allele most commonly found in natural populations or used as the standard reference; often denoted with a “+” (e.g., a+).
- Mutant allele: a variant that differs from the wild-type, often producing an altered phenotype.
- Conserved: a term describing sequences or residues that remain similar across species due to evolutionary constraint, not a label for the “normal” allele.
- Liberal: not a genetics term for allele types.

2) Step-by-step reasoning
- The question asks for the term naming the “original, common, or ‘normal’ version of a gene.”
- Compare each option with definitions: “mutant” denotes a change from normal, so it is the opposite. “Conserved” refers to evolutionary similarity, not the common allele within a population. “Liberal” is irrelevant. “Wild” (wild-type) matches the definition directly.

3) Intermediate steps (conceptual mapping)
- original/common/normal → commonly used synonym in genetics → wild-type allele
- wild-type commonly used in model organisms (e.g., Drosophila red eyes are wild-type; white eyes are mutant)

4) Why the correct answer is correct
- “Wild” (as shorthand for wild-type) is the conventional term in genetics for the allele that represents the standard or most common form in nature or the reference strain. It denotes the baseline against which mutant alleles are compared.

5) Why the other options are incorrect
- Mutant: indicates a changed allele producing a different phenotype, not the original common form.
- Conserved: describes sequence similarity across species, not the common allele label.
- Liberal: unrelated to genetic allele terminology.

6) Conclusion
Therefore, the correct answer is wild, matching the provided answer.

47. The original, common, or “normal” version of a gene is called the _________ type allele.单项选择题

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