The Claisen condensation first forms an ion which undergoes a to give the beta-ketoester. This product immediately undergoes an acid base reaction because it's pKa is about which is favored over the ester who's pKa is about . Multiple fill-in-the-blank
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Assign each of these statements as True or False. True Intramolecular Claisen condensations prefer 5 or 6 member rings. False Using a ketone as an enolate in a Claisen condensation gives a beta-diester. True Claisen condensations require 1 or more alpha H to form an enolate ion nucleophile to give a good yield. True The product of a Claisen condensation is more acidic than the starting material.
Which of these could be a nucleophile for a Claisen Condensation? (select all that apply)
The Claisen condensation is analogous to the reaction of aldehydes but with esters.
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