Question text SECTION B: FUNDAMENTALS OF BIOENERGETICS This section contains a total of 7 marks. You should allow 7-11 mins to answer the questions in this section. Q1-4. Consider the following structure of ATP to answer the following questions (1 mark each): Q1. Which one of the following factors does not contribute to the stability of ATP being lower than the stability of its hydrolysis products, ADP and Pi?Multiple choice 1 Question 2Charge repulsion in the ATP reactantIonization stabilisation of the ADP productThe cellular concentrations of ADP and Pi are lower than their equilibrium concentrationsResonance stabilisation of the inorganic phosphate (Pi) product Q2. The equilbrium constant (Keq) under standard conditions for the hydrolysis of ATP is 200,000 M. This would suggest the reaction is: Multiple choice 2 Question 2proceeding in reverse directionin equilibriumproceeding in forward direction Q3. However, this does not take into consideration the concentration of substrates/products within the cell. This is can be calculated by determining the reaction quotient, Q by: Multiple choice 3 Question 2[ATP] x [Pi] / [ADP][ATP] + [Pi] / [ADP][ADP] x [Pi] / [ATP][ADP] x [ATP] / [Pi] Q4. The reaction quotient (Q) for the hydrolysis of ATP is 0.0005 M. How does the cell maintain such a difference in Keq and Q? Multiple choice 4 Question 2tightly regulating the production of ATPconstantly exporting ADP from the cellmaintaining constant cellular temperature and pHcontinuously producing more ATP by catabolising nutrients Q5-6. The hydrolysis of ATP is often coupled to other reactions. For example: Glucose + Pi + H2O → Glucose-6-phosphate (ΔG'° = +14.8 kJ/mol) ADP + Pi →  ATP + H2O (ΔG'° = +30.5 kJ/mol)(The standard free-energy changes for the reactions are indicated in brackets) Q5. Given the information above, what is the overall ΔG'° for the following reaction? Glucose-6-phosphate + ADP → Glucose + ATP (2 marks). Multiple choice 5 Question 2+44.3 kJ/mol+16.7 kJ/mol-15.7 kJ/mol-44.3 kJ/mol+15.7 kJ/mol-16.7 kJ/mol Q6. Coupling reactions to ATP hydrolysis (1 mark): Multiple choice 6 Question 2shifts the system to equilbriumrarely occurs in metabolismallows exergonic reactions to occurallows endergonic reactions to occur Ensure that you have entered and checked all your answers before pressing "Next page" as you will not be able to return to this page and these questions.多项填空题