Question at position 25 What hormone triggers the resumption of meiosis in a primary oocyte just prior to ovulation?Follicle-stimulating hormone (FSH)ProgesteroneGonadotropin-releasing hormone (GnRH)EstrogenLuteinizing hormone (LH)

Question

BlackTom AI · Accepted Answer

To tackle this question, we evaluate what each hormone does in the context of oocyte maturation and ovulation.
Option 1: Follicle-stimulating hormone (FSH) – FSH primarily promotes follicle growth and development of the ovarian follicle, and it stimulates the initial follicular recruitment. While important for maturation, FSH is not the hormone that directly triggers the resumption of meiosis in a primary oocyte just before ovulation.
Option 2: Progesterone – Progesterone is mainly involved in preparing the endometrium for implantation and maintaining early pregnancy. It does not initiate the resumption of meiosis in the oocyte prior to ovulation, so this choice is not correct.
Option 3: Gonadotropin-releasing hormone (GnRH) – GnRH from the hypothalamus stimulates the anterior pituitary to release FSH and LH. It does not itself cause the resumption of meiosis in the oocyte; rather, it acts upstream to drive gonadotropin release.
Option 4: Estrogen – Estrogen has several roles in the reproductive cycle, including feedback regulation and endometrial effects, but it is not the direct trigger that resumes meiosis in a primary oocyte right before ovulation.
Option 5: Luteinizing hormone (LH) – The LH surge is the key signal that triggers the resumption of meiosis I in the primary oocyte, leading to its progression toward ovulation. This surge initiates meiotic activity and precedes ovulation.
In summary, the correct mechanistic driver for resuming meiosis in the primary oocyte just prior to ovulation is the LH surge, while the other hormones play supportive or indirect roles in follicle development, hormonal regulation, or endometrial preparation.

Question at position 25 What hormone triggers the resumption of meiosis in a primary oocyte just prior to ovulation?Follicle-stimulating hormone (FSH)ProgesteroneGonadotropin-releasing hormone (GnRH)EstrogenLuteinizing hormone (LH)Single choice

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