Which statement best explains how hydrophobic and hydrophilic amino acid residues influence protein folding in an aqueous environment?Single choice

A

Hydrophilic residues are usually buried in the protein core, while hydrophobic residues are usually exposed to water

B

Hydrophilic residues are the main determinants of protein folding, whereas hydrophobic residues play only a minor structural role

C

Hydrophobic residues are usually buried in the protein core, while hydrophilic residues are usually exposed to water

D

Hydrophilic residues always form covalent bonds with water, whereas hydrophobic residues cannot participate in any intermolecular interactions

E

Hydrophobic and hydrophilic residues are distributed randomly because folding is determined only by peptide bond formation

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