There are 3 parts to this question.[Fill in the blank] Describe FIVE (5) barriers to drug reaching tissues inside the eye after topical administration in eye drops.[Fill in the blank] Describe formulation or other approaches that can be used to overcome the barriers to effective topical administration to the front of the eye for treating ocular conditions.[Fill in the blank] Provide THREE (3) reasons why the pH of a formulation applied to the surface of the eye might be important?[Fill in the blank]Multiple fill-in-the-blank