What happens during a dominant modifier screen in the fly?

Question

BlackTom AI · Accepted Answer

In a dominant modifier screen in Drosophila genetics, researchers look for mutations that change the phenotype of an existing sensitised background. 
Option a: 'A phenotype is altered when performed on a sensitised background' correctly reflects the core idea of a dominant modifier screen, where a secondary mutation modifies an already altered or stressed phenotype, revealing interaction with the pathway or process of interest. 
Option b: 'A gene is deleted if it lies in the same pathway as another gene' describes a concept more aligned with epistasis or synthetic lethality, not specifically how a dominant modifier screen is defined. Modifier screens do not automatically imply gene deletion or a constraint about pathway co-location. 
Option c: 'Flies that are heterozygous for a mutation are converted to homozygotes' describes homozygous rescue or balancer/gene conversion schemes, not the aim of modifier screening, which seeks dominant effects on a sensitised background rather than converting zygosity. 
Option d: 'The screen is conducted to identify recessive alleles' is misleading because dominant modifier screens are specifically designed to reveal dominant interactions that modify a phenotype in the presence of another mutation or sensitised state; while recessive alleles can be identified in other types of screens, this option does not capture the defining purpose of a dominant modifier screen. 
Overall, the key misconception to avoid is thinking the screen’s purpose is about deletions, homozygosity changes, or solely recessive discovery; the essential feature is altering a phenotype in a sensitised background through dominant modification.

What happens during a dominant modifier screen in the fly?Single choice

Similar Questions

What is a genetic suppressor screen?

The history of the Nation of Islam (NOI) reveals that they seek recruits from prison.

Malcolm was president of his 6th grade class, he was one of several Blacks students in his school; a straight “A” student, and well like by his peers.

E.D. Nixon graduated from Howard University, majoring in political science.

Sharon Collins links the rise of Black professions to market efficiency. In other words, the labor market success of the Black professional elite is tied to market efficiency.

Regarding the role of race and class in structing the Black community, for those who saw race as a dominant factor --- discrimination was a key obstacle to Black economic development and attainment.

According to Malcolm, what was his last school-grade completed?

Malcolm’s father was a Baptist minister, very outspoken and a ________________.

More Practical Tools for Students Powered by AI Study Helper

Homework AI Solver

Stylized AI Paper Writer

Plagiarism Checker Assistant

Citation AI Academic Writing Tool

In-Class Translation Assistant

AI Note Generator

AI Quiz Answers

Past Exam Questions from University Test Bank

Smart Practice Assistant

Adaptive Practice

Making Your Study Simpler