Epoxides react with nucleophiles on the more substituted side in acidic conditions. This will invert the stereochemistry at the reacting carbon and will not invert the stereochemistry at the non-reacting carbon. This is a SN2 mechanism.Multiple dropdown selections
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Epoxides react with nucleophiles on the less substituted side in basic conditions. This will invert the stereochemistry at the reacting carbon and will not invert the stereochemistry at the non-reacting carbon. This is a SN2 mechanism.
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