Which of the following most accurately characterises the enteric nervous system (ENS) and its interaction with the rest of the nervous system?Single choice

A. The ENS primarily controls reflexes in skeletal muscles and relies entirely on input from the sympathetic nervous system.

B. Although part of the peripheral nervous system, the ENS is sometimes called the “second brain” because it can independently regulate complex digestive functions.

C. The ENS is a cluster of neurons located in the liver and pancreas that initiates nutrient absorption and bile production.

D. The ENS is inactive unless stimulated by signals from the cerebral cortex, especially during times of physical stress.