Neurogenesis can be inhibited by Cytosine beta-D-arabinofuanoside (Ara-C). How does Ara-C work? 阿糖胞苷(Ara-C)可以抑制神经发生。Ara-C 的作用机制是什么?Single choice

A

It inhibits RNA activity by increasing the production of neuron-specific RNAase activity 它通过增加神经元特异性 RNA 酶活性的产生来抑制 RNA 活性。

B

It is incorporated into DNA, inhibiting DNA replication by forming cleavage complexes with topoisomerase I, resulting in DNA fragmentation 它掺入 DNA 中,通过与拓扑异构酶 I 形成切割复合物来抑制 DNA 复制,导致 DNA 片段化。

C

It triggers a redox reaction and increases production of toxic superoxide free-radicals in immature neurons 它会引发氧化还原反应,并增加未成熟神经元中有毒超氧自由基的产生。

D

It binds to DNA and prevents its transcription into messenger RNA 它与 DNA 结合,阻止其转录成信使 RNA。

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